Let’s Break It Down: What’s Inside Vital Plan RESTORE180?
If you have spent any amount of time navigating Lyme disease or another complex chronic illness, you probably have a supplement cabinet that tells a story.
There may be products you take every day, products you tried once, products you cannot remember why you bought, and at least a few bottles recommended by someone along the way that you never quite figured out how to incorporate into everything else.
This is one of the reasons Vital Plan RESTORE180 caught our attention.
RESTORE180 is not a single supplement or another collection of products that you are left to figure out on your own. Developed by Dr. Bill Rawls, RESTORE180 is a six month program that organizes specific supplements into three progressive phases. Each phase is designed to build upon the previous one, beginning with foundational support, progressing into detoxification and gut support, and eventually focusing more heavily on cellular resilience, microbial balance, energy, and recovery.
The complete program includes eight different Vital Plan products, but you do not take all eight at the same time.
So what exactly are all of these supplements, what are they designed to support, and why are they included at different points in the program?
Let’s break it down.
First, How Does RESTORE180 Work?
RESTORE180 is divided into three phases that take place over 180 days.
The first two months are called Calm and Stabilize. Months three and four move into Detoxify and Balance. The final two months are called Rebuild and Restore.
Rather than completely changing the protocol every two months, certain foundational products continue from one phase to another while others are introduced or removed as the focus of the program changes.
RESTORE180 also includes educational resources, health coaching and access to the Vital Plan community. Participants receive three individual coaching sessions during the program, one during each phase, as well as an additional graduate coaching session during the final month.
Vital Plan RESTORE180 at a Glance
Length: 180 days
Phases: Three
Phase One: Calm and Stabilize
Phase Two: Detoxify and Balance
Phase Three: Rebuild and Restore
Supplements: Eight different Vital Plan supplements used throughout the program
Coaching: Individual coaching during each phase plus a graduate session
Price at Publication: $299 per month at the time of publication
Now let’s look at what is actually inside the supplement protocol.
Phase One: Calm and Stabilize
The first two months of RESTORE180 are intended to establish a foundation before moving more deeply into other areas of the program.
During the first month, participants receive Daily Multi Plus, HPA Balance, Mitochondrial Support and Biome Boost.
Pure Chlorella is added during the second month.
Daily Multi Plus
Daily Multi Plus is one of the foundational products that remains in the RESTORE180 protocol throughout all six months.
This is not simply a standard multivitamin. The formula combines 25 vitamins and minerals with herbal and plant-based compounds that provide additional antioxidant and cellular support.
The formula includes vitamins C, D and E, activated B vitamins and minerals, along with Japanese knotweed, pine bark extract, milk thistle and hawthorn.
For people living with chronic illness, the nutritional foundation matters. Years of restricted diets, gastrointestinal problems, poor appetite, chronic physiological stress and other factors can make maintaining optimal nutrient intake more complicated.
Daily Multi Plus is designed to provide broad nutritional and antioxidant support while the other parts of the RESTORE180 protocol change throughout the six months.
HPA Balance
HPA Balance is introduced immediately during Phase One and continues through Phase Two.
The HPA axis, or hypothalamic pituitary adrenal axis, is one of the systems involved in regulating the body's response to stress.
For people who have lived with chronic illness for years, stress is not limited to emotional stress: infection, inflammation, disrupted sleep, pain, environmental exposures and the physical demands of illness can all place stress on the body.
HPA Balance combines Sensoril ashwagandha extract, Relora tree bark extracts and L-theanine. These ingredients are used to support the body's stress response, relaxation, focus, and sleep quality.
Its placement at the beginning of RESTORE180 reflects the program's broader philosophy that creating greater physiological stability is an important foundation for the work that follows.
Mitochondrial Support
Mitochondrial Support is another foundational product that remains in the protocol for all six months.
Mitochondria help cells convert nutrients into usable energy. Because nearly everything the body does requires energy, mitochondrial health has become an important area of interest in conversations about chronic illness, fatigue and recovery.
Vital Plan's Mitochondrial Support combines five familiar ingredients: glutathione, N acetyl cysteine, alpha lipoic acid, vitamin C and Coenzyme Q10.
Together, these nutrients provide antioxidant support while supporting mitochondrial function, cellular energy production and the body's normal detoxification processes.
Glutathione is particularly noteworthy in the context of detoxification because it plays an important role in the body's antioxidant defenses and normal liver detoxification processes. N acetyl cysteine is also used by the body as a precursor for glutathione production.
Rather than introducing mitochondrial support only during the final rebuilding stage, RESTORE180 includes it from the beginning and continues it throughout the entire program.
Biome Boost
This is where the RESTORE180 protocol becomes especially interesting for the Lyme community.
Biome Boost is a liquid herbal formula containing cryptolepis, houttuynia, prickly ash, Chinese salvia and neem.
If you have spent years in the Lyme disease world, some of those names may already be very familiar.
Vital Plan designed Biome Boost to support microbial balance, immune function and the body's microbiome. Rather than thinking of the microbiome exclusively as the bacteria living inside the gastrointestinal tract, Vital Plan takes a broader view of microbial balance throughout the body.
Biome Boost begins during the first month and continues through the first four months of RESTORE180.
The inclusion of this formula early in the program means microbial support is not being saved until the end. Instead, it is introduced alongside nutritional, mitochondrial and stress response support.
Pure Chlorella
Pure Chlorella enters the program during month two.
Chlorella is a nutrient dense freshwater green algae that provides protein, vitamins, minerals, chlorophyll and other naturally occurring compounds.
It is particularly popular within the chronic illness community for its role in detoxification support.
Vital Plan uses Pure Chlorella to support the body's natural detoxification processes as well as gastrointestinal and microbiome health. Its introduction during the second month provides an interesting transition between the Calm and Stabilize phase and the more detoxification focused phase that follows.
For people with Lyme disease and other complex chronic illnesses, detoxification support can be an important part of a comprehensive wellness plan. Individual tolerance can vary significantly, which is one reason introducing strategies gradually may be helpful.
Phase Two: Detoxify and Balance
During months three and four, RESTORE180 moves into its Detoxify and Balance phase.
Daily Multi Plus, HPA Balance, Mitochondrial Support and Biome Boost remain in the protocol, while Gut Balance is introduced.
The emphasis during this phase expands to include gastrointestinal health, digestion, elimination and detoxification.
Gut Balance
Gut Balance combines three primary herbal ingredients: slippery elm bark, berberine and dandelion extract.
Each serves a somewhat different purpose within the formula.
Slippery elm has a long history of traditional use for soothing and supporting the gastrointestinal tract.
Berberine is a naturally occurring plant compound found in several herbs and has been extensively studied for its effects on microbial balance and metabolic health.
Dandelion has traditionally been used to support digestion and normal liver and gallbladder function.
Together, Vital Plan uses these ingredients to support the intestinal lining, healthy gut flora, digestion, normal bowel function and the body's detoxification processes.
The timing makes sense within the overall structure of RESTORE180. Detoxification is not only about processing substances. The body also needs effective pathways through which waste can ultimately be eliminated.
Supporting digestion, bowel function and gastrointestinal health therefore becomes an important part of the Detoxify and Balance phase.
Phase Three: Rebuild and Restore
Months five and six mark the biggest change in the RESTORE180 supplement protocol.
HPA Balance, Biome Boost and Gut Balance are removed from the core protocol.
Daily Multi Plus and Mitochondrial Support remain, while two different herbal formulas are introduced: Adaptogen Recovery and Advanced Biotic.
The focus now shifts toward resilience, energy, immune support and longer term microbial balance.
Adaptogen Recovery
Adaptogen Recovery combines Chinese skullcap, cordyceps, reishi mushroom and rehmannia.
These herbs are classified or commonly used as adaptogenic and resilience supporting herbs, although each has its own unique properties and history of use.
Adaptogens are generally used to support the body's ability to respond and adapt to physical and physiological stress.
Cordyceps and reishi mushrooms have long histories of traditional use and are frequently used to support immune health, stamina and resilience. Chinese skullcap and rehmannia also have extensive histories within traditional herbal medicine.
Vital Plan positions Adaptogen Recovery around immune balance, stamina, metabolic and hormonal balance, and resilience to stress.
Its introduction during the final two months reflects an important distinction in the RESTORE180 philosophy. Managing the factors contributing to chronic illness is only part of the process. At some point, the body also needs resources that support rebuilding and resilience.
Advanced Biotic
Advanced Biotic is the second major formula introduced during the Rebuild and Restore phase.
It contains andrographis, berberine, cat's claw, Japanese knotweed, garlic and sarsaparilla.
Once again, people familiar with herbal approaches to Lyme disease will probably recognize several of these ingredients.
Vital Plan designed Advanced Biotic to support microbiome balance and normal immune function while also providing antioxidant, liver, respiratory and lymphatic support.
The combination is particularly interesting because RESTORE180 does not abandon microbial support during the rebuilding phase. Instead, the type of herbal support changes.
Biome Boost provides microbial support during the first four months. Advanced Biotic takes its place during months five and six while the foundational Daily Multi Plus and Mitochondrial Support remain.
Why Does RESTORE180 Change the Supplements Throughout the Program?
This may be the most interesting part of RESTORE180.
Many chronic illness patients are accustomed to protocols that involve starting a large number of supplements at once and continuing them indefinitely.
RESTORE180 takes a different approach.
The supplement protocol evolves throughout the six months based on the focus of each phase.
The program begins by establishing nutritional, cellular, stress response and microbial support. Detoxification support is gradually incorporated, followed by more targeted gastrointestinal support. During the final phase, the protocol shifts toward adaptogens, immune support, microbial balance and rebuilding resilience.
Daily Multi Plus and Mitochondrial Support remain throughout the entire process, creating a nutritional and cellular foundation underneath the changing herbal formulas.
For someone already overwhelmed by managing a complicated chronic illness protocol, there is something appealing about knowing what you are taking, why you are taking it and where it fits into a larger plan.
RESTORE180 Is More Than the Supplements
It is also important to understand that the products are only one part of RESTORE180.
The six month membership includes three 30 minute individual coaching sessions, with one coaching session available during each phase. Participants also receive a graduate coaching session during month six to help determine what comes next.
The program includes educational lessons, wellness resources, group coaching opportunities and access to a private RESTORE180 community through the Vital Plan Network.
That additional structure is an important distinction between purchasing several Vital Plan supplements individually and participating in RESTORE180.
You are not simply receiving a box of supplements every month and being left to determine what to do with them.
How Much Does Vital Plan RESTORE180 Cost?
At the time of publication, RESTORE180is priced at $299 per month and is billed monthly for the six month program.
That brings the standard six month cost to $1,794.
The program includes the phase specific supplements, educational materials, coaching and community access. Vital Plan also currently offers free shipping and states that participants can cancel the program.
Because pricing and promotions can change, we recommend checking the Vital Plan website for the current program price before enrolling.
Learn More About Vital Plan Here on Lyme Advise →
Who Might Be Interested in RESTORE180?
RESTORE180 may be particularly interesting to people who are looking for a structured herbal wellness program rather than trying to assemble an extensive supplement protocol on their own.
For members of the Lyme disease community, several of the herbs used throughout RESTORE180will already be familiar, including Japanese knotweed, cat's claw, cryptolepis, houttuynia, andrographis, berberine and sarsaparilla.
The program may also appeal to people who want education and coaching alongside their supplement protocol or who find themselves overwhelmed by trying to decide what to take and when to take it.
However, RESTORE180 is a wellness program and is not a replacement for individualized medical care or treatment for Lyme disease or another medical condition.
Herbs and nutritional supplements can interact with medications and may not be appropriate for everyone. People who are pregnant or breastfeeding, taking prescription medications, managing significant medical conditions, or working through a complicated treatment protocol should discuss new supplements with their healthcare provider.
What We Like About the RESTORE180 Approach
One of the realities of living with chronic illness is that supplement protocols can become complicated very quickly.
It is not unusual for someone who has been sick for years to accumulate dozens of products recommended by different practitioners, books, podcasts, social media posts and other patients.
Eventually, it can become difficult to remember why each supplement was added in the first place.
What we find interesting about RESTORE180 is the structure.
The program does not treat recovery as one single intervention. It creates a progression that begins with foundational support, incorporates detoxification and gastrointestinal health, and eventually shifts toward rebuilding resilience.
We also appreciate that the supplements are paired with education and access to health coaching rather than simply being shipped to participants without additional guidance.
No single program will be appropriate for every person with Lyme disease or complex chronic illness. There is simply too much individual variation for that to be realistic.
However, for people interested in Dr. Bill Rawls' herbal approach who would prefer a structured program rather than piecing together individual products themselves, RESTORE180 provides an interesting way to do that.
And now, when you look at the eight bottles involved in RESTORE180, you know exactly why each one is there.
SHOP RESTORE180 HERE
This article is for educational purposes only and is not intended to diagnose, treat, cure, or prevent Lyme disease or any other medical condition. Supplements and herbs can cause side effects and interact with medications. Talk with a qualified healthcare professional before beginning a new supplement or wellness program.
FAQs
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Vital Plan RESTORE180 is a six month wellness program developed by Dr. Bill Rawls that combines herbal and nutritional supplements with education, health coaching and community support. The program progresses through three phases called Calm and Stabilize, Detoxify and Balance, and Rebuild and Restore.
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RESTORE180 lasts 180 days, or approximately six months. The program is divided into three phases, with each phase lasting approximately two months.
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RESTORE180 uses eight different Vital Plan products and formulas throughout the six month program. Participants do not take all eight products at the same time. The supplement protocol changes as they move through the three phases.
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RESTORE180 is a wellness program and is not a pharmacological medical treatment for Lyme disease. However, several herbs included in the program, including Japanese knotweed, cat's claw, cryptolepis, houttuynia and andrographis, may already be familiar to people who have explored herbal approaches within the Lyme disease community.
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At the time this article was published, RESTORE180 was priced at $299 per month for six months. Pricing and promotions can change, so readers should check Vital Plan for current pricing.