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HBOT, or hyperbaric oxygen therapy, involves breathing pure oxygen in a pressurized room or tube. In a hyperbaric oxygen therapy chamber, the air pressure is increased to three times higher than normal air pressure. Under these conditions, your lungs can gather more oxygen than would be possible breathing pure oxygen at normal air pressure. Your blood carries this oxygen throughout your body helping to fight bacteria and stimulate the release of substances called growth factors and stem cells, which promote healing.